Blar i forfatter "Roland, Marie Cecilie"

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    • Elevated cholesteryl ester transfer protein activity early in pregnancy predicts prediabetes 5 years later 

      Ueland, Thor; Roland, Marie Cecilie; Michelsen, Annika; Godang, Kristin; Aukrust, Pål; Henriksen, Tore; Bollerslev, Jens; Lekva, Tove (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-29)
      <i>Context</i> - Cholesteryl ester transfer protein (CETP) regulates high-density lipoprotein (HDL) cholesterol levels and interaction between glucose, and HDL metabolism is central in the development of diabetes.<p> <p><i>Objective</i> - We hypothesized that CETP levels would be regulated in diabetic pregnancies. We tested the hypothesis by evaluating CETP activity measured multiple times during ...

    • Platelet and mitochondrial RNA is decreased in plasma-derived extracellular vesicles in women with preeclampsia—an exploratory study 

      Lekva, Tove; Sundaram, Arvind; Roland, Marie Cecilie; Åsheim, June; Michelsen, Annika Elisabet; Norwitz, Errol R.; Aukrust, Pål; Gilfillan, Gregor; Ueland, Thor (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-23)
      Background - Circulating extracellular vesicles (EVs) are increased in preeclampsia (PE) and are associated with severity and progression. We examined in this exploratory cohort study if the mRNAs and long noncoding RNAs (lncRNAs) in plasma-derived EVs were dysregulated in PE compared to normal pregnancy and display different temporal patterns during gestation.<p> <p>Methods - We isolated EVs ...